The Enzymatic Transfer of Strained Ring Containing Bioothrogonal Tags

Name of Award

3M grant

Date Awarded




Project Description

James Wollack, PhD, Associate Professor, was awarded a 3M grant in the amount of $30,995 to study how biological chemists can conduct chemical reactions between specified numbers of materials in biological systems containing numerous other reactive materials without harming the system being studied?

The most common ways to conduct bioorthogonal reactions—reactions that can proceed independently despite being in the midst of other potentially reactive materials—involves copper catalysts and can be toxic for the biological system being studied. This study looks at new ways to conduct bioorthogonal reactions without toxic copper catalysts. It will specifically determine the concentrations of material that necessary for such reactions to occur.

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